Another Clinical Trial Possibility
As our son, Charlie, continues to look for a clinical trial that would suit Gorman, one has turned up at University of Florida in Gainesville and it sounds very encouraging, IF he qualifies. It is referred to as EGFRvIII and is being conducted at 200 sites worldwide. It’s complicated: about one-third of glioblastoma tumors (that’s what Gorman has) contain this protein called EGFRvIII. This clinical trial involves an experimental vaccine that, hopefully, activates the immune system to fight the cancer. This trial is in Phase 3, which means it has shown promising results thus far. As with so many of these trials, this one is a randomized, double-blind trial so two-thirds of the participants will receive the vaccine and one-third will receive a placebo. As frustrating as it is, that appears to be pretty standard procedure for clinical trials. So first of all, Gorman has to fall in that 30 percent of GBM tumors containing the right protein (EGFRvIII). We should learn next week if he qualifies. Then we have to hope that he’ll be among those receiving the vaccine. He has made me promise that, if he doesn’t get in, I will not fall apart like I did over the UAB trial and I have dutifully promised that I won’t. I like to think I’m stronger after that first experience; at least I hope I am.
In the meantime, today we began week five of chemoradiation. We’re glad for the treatment but will be happy when the radiation part is over. It is wearing him down. This past weekend, when 30,000 tourists descended on Fairhope for the annual Arts & Crafts Fair, we left and went to the beach, where we did absolutely nothing but sleep and rest. It was a nice little gift from God. And now we’re back at it, kicking this cancer in the #*#*!!